Biobanking of Human Biospecimens: Lessons from 25 Years of Biobanking Experience

Biobanking of Human Biospecimens: Lessons from 25 Years of Biobanking Experience Over the past 25 years, biobanks of human specimens have become a cornerstone for research on human health and have empowered the 'omics 'revolution that characterizes biomedical science in the XXIst Century. Today, biobanking of human specimens is a critical component of the interface between clinical practice and translational research, supporting the discovery and validation of new biomarkers of disease etiology, risk, early detection, diagnosis, prognosis, prediction and relapse. With the development of personalized medicine, biobanking of cryopreserved specimens has become standard practice in order to investigate genetic, transcriptomic, proteomic, metabolomics and immunological biomarkers useful to inform caregivers for therapeutic decisions. Data generated from biobanked specimens represent a rapidly growing and highly valuable resource, participating in the emergence of Big Data Medicine. With the development of large computing capabilities and artificial intelligence, dataassociated with biobanked specimens constitute a unique resource for the discovery and validation of new biomarkers and therapeutically actionable targets. Interconnecting, interoperating and sharing this data have become major issues for national health systems, raising enormous stakes as well as major societal, legal and cybersecurity challenges in terms of compliance with the protection of personal sensitive information.This book project is the second part of an initiative launched in 2012 to produce a published corpus of knowledge encompassing all aspects of human biobanking as a central practice for research and medicine. The first volume, published in 2017, is entitled: Human Biobanking: Principles and Practice. This first volume compiled a series of high level contributions overseeing the main developments that carried the progression of human biobanking as a research and biotechnological field over the past two decades. This new book project will constitutede f [...] Wydawnictwo: Springer Rok wydania: 2021 Okładka: twarda Liczba stron: 206 Wymiary: 23.5 x 15.5 cm Ilustracje: 39 Illustrations, color; 5 Illustrations, black and white; X, 206 p. 44 illus., 39 illus. in color. Język: angielski ISBN: 9783030559007