Modelling Metabolism with Mathematica Using the human erythrocyte as an example, this book presents the approaches, methods, tools, and algorithms for modelling the chemical-dynamics of metabolic pathways. The authors explain the concepts underpinning the deterministic theory of chemical and enzyme kinetics in such a way that readers will be able to formulate their own models of time-dependent metabolic systems. They present a graded series of computer models of metabolic pathways leading up to that of human erythrocyte metabolism, and they document a consistent set of rate equations and associated kinetic parameters relevant to the human erythrocyte, which makes the book of particular interest to readers involved with red cell enzymology. With the advent of sophisticated general programming environments like Mathematica, the task of developing new models of metabolism and visualizing their responses has become accessible to students of biochemistry and the life sciences in general. Modelling Metabolism with Mathematica presents the approaches, methods, tools, and algorithms for modelling the chemical-dynamics of metabolic pathways. The authors explain the concepts underpinning the deterministic theory of chemical and enzyme kinetics, present a graded series of computer models of metabolic pathways leading up to that of the human erythrocyte, and document a consistent set of rate equations and associated kinetic parameters.The experimental and theoretical study of metabolism in mammalian cells has a long and fruitful history, but our understanding of cellular metabolism at the molecular level is far from complete. This book enables its readers to formulate their own models of time-dependent metabolic systems and aids them in the quest for the many fundamental and clinically relevant discoveries that remain to be made. Autor: Peter Mulquiney, Philip W. Kuchel Wydawnictwo: Taylor & Francis Rok wydania: 2019 Okładka: miękka Liczba stron: 328 Wymiary: 23.4 x 15.6 cm Język: angielski ISBN: 9780367395223